Death by a Thousand Cuts: The Fading Influence of El Chapo Guzmán's Family
The name Guzmán is cartel royalty. But every dynasty dwindles. Despite the Chapitos being one of Mexico's most powerful factions, arrests, killings, and extradition have taken a steady toll.
Isaí Martínez Cepeda is not the most important Guzmán to be arrested. He is not in the top ten. On 26 May, Mexican Security Secretary Omar García Harfuch announced that an interagency task force had detained the man known as El Chinacate, a nephew of Joaquín “El Chapo” Guzmán Loera, in a residential street in the Casa Blanca neighbourhood of Nogales, Sonora.
Isaí was under an active US extradition order and described him as a logistical coordinator for Los Chapitos, accused of running synthetic-drug production lines into the United States and Costa Rica. Investigators said that he had brokered the sale of 10,000 fentanyl pills to the US in 2025.
Isaí is not central to the Chapitos, the faction of the Sinaloa Cartel run by El Chapo’s sons. At most, he is mid-tier. But his arrest is a useful occasion to take stock of the Guzmán family more broadly as the dragnet reaches its lower rungs.
El Chapo’s family is not done. The Chapitos remain one of the dominant forces in the Mexican criminal landscape and in the cross-border fentanyl trade. Iván Archivaldo and Jesús Alfredo Guzmán Salazar still run the faction from the Sierra Madre. But there’s only two of them left. Ovidio and Joaquín are in present.
El Chapo’s family is not done, but it is dwindling.
Here’s how it happened.


